IN VITRO CHARACTERIZATION OF THE PHARMACOLOGICAL PROPERTIES OF THE ANTI-CANCER CHELATOR, BP4ET, AND ITS PHASE I METABOLITES.

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites.

Cancer cells have a high iron requirement and many experimental studies, as well as clinical trials, have demonstrated that iron chelators are potential anti-cancer agents.The ligand, 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone (Bp4eT), demonstrates both potent anti-neoplastic and anti-retroviral properties.In this study, Bp4eT and its recently i

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Improving Nitrogen Use Efficiency in Aerobic Rice Based on Insights Into the Ecophysiology of Archaeal and Bacterial Ammonia Oxidizers

The abundance and structural composition of nitrogen (N) Dice transformation-related microbial communities under certain environmental conditions provide sufficient information about N cycle under different soil conditions.This study aims to explore the major challenge of low N use efficiency (NUE) and N dynamics in aerobic rice systems and reveal

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Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

Cells release heterogeneous nano-sized vesicles either Sweatshirt as exosomes, being derived from endosomal compartments, or through budding from the plasma membrane as so-called microvesicles, commonly referred to as extracellular vesicles (EVs).EVs are known for their important roles in mammalian physiology and disease pathogenesis and provide a

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